Tobacco Enema Kit, 1774
Made by Evans & Co of London, this apparatus was used to revive people who were ‘apparently dead’, by making use of tobacco’s stimulant qualities. The bellows were used to blow tobacco smoke up the rectum (or into the lungs) … Tobacco enemas were popular from the 17th to the early 19th century. [Source]
Tobacco was recognised as a medicine soon after it was first imported from the New World, and tobacco smoke was used by western medical practitioners as a tool against cold and drowsiness, but applying it by enema was a technique appropriated from the North American Indians. The procedure was [also] used to treat gut pain, and attempts were often made to resuscitate victims of near drowning. Liquid tobacco enemas were often given to ease the symptoms of a hernia.
During the early 19th century the practice fell into decline, when it was discovered that the principal active agent in tobacco smoke, nicotine, is poisonous. [Source]